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"Edit your settings.py file to include django.middleware.http.SetRemoteAddrFromForwardedFor in MIDDLEWARE_CLASSES. This allows your Django application to use the real IP address of the client instead of 127.0.0.1 from your nginx proxy. It sets Django's request.META['REMOTE_ADDR'] to be request.META['HTTP_X_FORWARDED_FOR'] which we set above in nginx's proxy.conf."

Source: http://www.saltycrane.com/blog/2009/04/notes-using-nginx-mod_python-and-...